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The NCERC is located in University Park, a research park on the southern edge of the Southern Illinois University in Edwardsville, Illinois. The Center is 20 miles from downtown Saint Louis and 25 minutes from Lambert International Airport in Saint Louis, Missouri.

Saint Louis is the center of the Biobelt; home to the Donald Danforth Plant Sciences Center, the Missouri Botanical Garden, Monsanto, Washington University, the National Corn Growers Association, the United Soybean Association and numerous life science start up companies.

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For overnight or extended stay in the area while working or visiting the Center, the following accommodations are recommended.

Hampton Inn
5723 Heritage Crossing Drive
Glen Carbon, IL; 618-589-5000

Country Hearth Inn & Suites
1013 Plummer Drive
Edwardsville, Illinois; 618-656-7829

Drury Inn
602 N Bluff Road
Collinsville, Illinois; 618-346-7700 {Approximately 15 miles}

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